Liposarcoma of the Thigh

Unknown Musculoskeletal Case 5


84 y/o man with mass in leg.

Image Findings

A large mass is seen in the medial thigh. This mass is very bright on T1-weighted images. It is somewhat bright on the T2-weighted fast spin echo images. With fat suppression and gadolinum, much of the signal of the mass suppresses, though significant enhancement is still seen.

Differential Diagnosis



Liposarcoma is one the most common soft tissue sarcoma with a peak incidence in the 5th decade. It usually involves the thigh, lower leg, retroperitoneum, or buttock. Metastases are uncommon with well differentiated tumors but occur more frequently with pleomorphic and round cell types. Lungs and viscera are the most common sites for metastases.
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Last modified April 18, 1995
Copyright 1995 Ray Ballinger, University of Florida and VA Medical Center, Gainesville, FL.