Although MRI was initially hoped to provide a means of making definitive
diagnoses noninvasively, we have found that the addition of contrast agents
in many cases improves our sensitivity and/or specificity. Paul Lauterbur
and his associated were the first to demonstrate the feasibility of using
paramagnetic contrast agents to improve tissue discrimination in MRI. I have
somewhat arbitrarily grouped this topic into the subjects listed below. If
you would like to review the differences between diamagnetic, paramagnetic,
superparamagnetic, and ferromagnetic; look over the magnetism section.