MRI Contrast Agents

Although MRI was initially hoped to provide a means of making definitive diagnoses noninvasively, we have found that the addition of contrast agents in many cases improves our sensitivity and/or specificity. Paul Lauterbur and his associated were the first to demonstrate the feasibility of using paramagnetic contrast agents to improve tissue discrimination in MRI. I have somewhat arbitrarily grouped this topic into the subjects listed below. If you would like to review the differences between diamagnetic, paramagnetic, superparamagnetic, and ferromagnetic; look over the magnetism section.

Last modified 12 September 2009